Research Highlights: Highlights from the latest articles in immunotherapy
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چکیده
منابع مشابه
Highlights From the Latest in Diabetes Research
It is widely accepted that exercise is benefi cial to health, yet national survey data indicate that 36.2% of American adults do not engage in any leisure-time physical activity. Further, numerous cross-sectional and longitudinal studies have quantifi ed relationships between physical activity and various outcomes including diabetes, cardiovascular disease, and mortality, with most showing an i...
متن کاملHighlights From the Latest in Diabetes Research
A new report provides intriguing new data on the potential role of cellular senescence in aging and metabolic dysfunction. Aging is accompanied by development of chronic diseases as well as loss of function, changes in body composition, and insulin resistance. Despite these well-recognized patterns, the specifi c mechanisms by which aging increases risk of disease and loss of function are poorl...
متن کاملHighlights From the Latest in Diabetes Research
There is no doubt that a Western lifestyle, including excess caloric intake and limited physical activity, increases the risk of type 2 diabetes. Understanding the risks associated with specifi c aspects of unfavorable lifestyle choices may facilitate the development of prevention efforts that are tailored to the needs of specifi c patients. One feature of the Western diet is a relatively high ...
متن کاملHighlights From the Latest in Diabetes Research
Circulating fatty acids (FAs) have an unclear relationship to insulin sensitivity. During fasting and exercise, FAs from white adipose tissue (WAT) lipolysis are delivered to peripheral tissue to meet energy needs. In obesity, excess circulating FAs are thought to drive the development of insulin resistance. Girousse et al., through a variety of in vivo and in vitro human and mouse studies, pro...
متن کاملHighlights From the Latest in Diabetes Research
Obesity and increased lipid deposition in ectopic tissues, such as the heart and skeletal muscle, are linked to insulin insensitivity and type 2 diabetes. Vascular endothelial growth factor B (VEGF-B) is expressed in highly metabolic tissues and acts through endothelial receptors on skeletal and cardiac muscle to increase fatty acid uptake and lipid deposition. Mice lacking Vegfb exhibit lower ...
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ژورنال
عنوان ژورنال: Immunotherapy
سال: 2012
ISSN: 1750-743X,1750-7448
DOI: 10.2217/imt.12.27